Publication Type: | Journal Article |
Year of Publication: | 2012 |
Authors: | H. - X. Li, Fan, J., Hu, W., Wang, C., Kitanaka, S., Li, H. - R. |
Journal: | J Tradit Complement Med |
Volume: | 2 |
Issue: | 2 |
Pagination: | 154-7 |
Date Published: | 2012 Apr |
ISSN: | 2225-4110 |
Abstract: | In vitro anti-allergic screening of medicinal herbal extracts revealed that the 80% acetone extract of the rhizome of Kadsura coccinea inhibited nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ (IFN-γ) activated murine macrophage like cell line, RAW264.7. Further fractionation of the EtOAc extract led to the isolation of one new 3,4-seco-lanostane type triterpene named kadsuracoccin acid A (1) together with two known triterpenes anwuweizonic acid (2) and neokadsuranic acid B (3). Compounds 1-3 did not exhibit any inhibitory activities for NO production and IFN-γ activation. |
Alternate Journal: | J Tradit Complement Med |
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