| Publication Type: | Journal Article |
| Year of Publication: | 2015 |
| Authors: | W. Su, Zhao, J., Yang, M., Yan, H. - W., Pang, T., Chen, S. - H., Huang, H. - Y., Zhang, S. - H., Ma, X. - C., Guo, D. - A., Khan, I. A., Wang, W. |
| Journal: | Bioorg Med Chem Lett |
| Volume: | 25 |
| Issue: | 7 |
| Pagination: | 1506-8 |
| Date Published: | 2015 Apr 1 |
| ISSN: | 1464-3405 |
| Abstract: | Coumarinlignan (1), possessing a unique coumarin-containing lignan skeleton, was isolated from the stems of Kadsura heteroclita. Its structure and absolute configuration were determined by spectroscopic techniques, especially 2D NMR and X-ray crystallographic data analyses. The proposed biosynthetic pathway is discussed. This new compound showed good anti-HBV activity against HBeAg and HBsAg, and moderate anti-fibrotic and neuroprotective activities. |
| DOI: | 10.1016/j.bmcl.2015.02.022 |
| Alternate Journal: | Bioorg. Med. Chem. Lett. |
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