Hodgsonia, Kadsura and Paris in Thailand

Conserved plants of Plant Genetic Conservation Project (RSPG)

Triterpenes from Kadsura coccinea.

Publication Type:Journal Article
Year of Publication:2012
Authors:H. - X. Li, Fan, J., Hu, W., Wang, C., Kitanaka, S., Li, H. - R.
Journal:J Tradit Complement Med
Date Published:2012 Apr

In vitro anti-allergic screening of medicinal herbal extracts revealed that the 80% acetone extract of the rhizome of Kadsura coccinea inhibited nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ (IFN-γ) activated murine macrophage like cell line, RAW264.7. Further fractionation of the EtOAc extract led to the isolation of one new 3,4-seco-lanostane type triterpene named kadsuracoccin acid A (1) together with two known triterpenes anwuweizonic acid (2) and neokadsuranic acid B (3). Compounds 1-3 did not exhibit any inhibitory activities for NO production and IFN-γ activation.

Alternate Journal:J Tradit Complement Med
Scratchpads developed and conceived by (alphabetical): Ed Baker, Katherine Bouton Alice Heaton Dimitris Koureas, Laurence Livermore, Dave Roberts, Simon Rycroft, Ben Scott, Vince Smith